In this interview, News Medical speaks to Assistant Professor Ryan Jackson about his latest work, published in tandem Nature papers, detailing the discovery of a new CRISPR immune system. Please can ...

This includes the labeling of the dCas9 protein, engineering of sgRNA, and the use of dCas9 orthologs from different bacterial species. CRISPR, clustered regularly interspaced short palindromic ...

Instead of permanently rewriting DNA, CRISPR-based activators attach to specific promoters and dial up endogenous genes that drive pluripotency, which lets researchers choreograph the transition from ...

Across all domains of life, immune defenses thwart invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens’ DNA and chop it up to ...