Researchers at Goethe University have elucidated the relationships among all 462 catalytic human E3 ligases; E3 ligases also support non-degradative functions. FRANKFURT. Maintaining cellular order is ...
Newco Outrun Therapeutics Ltd. has raised $10 million in a seed round to develop small-molecule E3 ubiquitin ligase inhibitors that prevent programmed protein degradation. The lead program targeting ...
An international team led by Australia’s Walter and Eliza Hall Institute (WEHI) has created the first authoritative atlas for a class of enzymes that regulate almost every cellular process in the ...
Exploring pediatric E3 ligases to enable targeted protein degradation therapies for childhood cancer
This article and associated images are based on a poster originally authored by Ashleigh Hill, Marie-Louise Francis, Viktoria Brachmaier, Egle Vaitone, Rachel Forfar and Sandra Kuemper and presented ...
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